UPDATE: I posted a video showing the picking for this lick. Visit http://www.learnblueslicks.com/2nd-most-important-guitar-lick/.
** Note: A higher res version is at http://www.learnblueslicks.com...along with the no. 1 greatest guitar lick **
Wow! That's a pretty bold statement, and it's only my opinion. However, I feel it's one of those licks that every great player uses over and over. YOU NEED TO KNOW THIS LICK! Hendrix, Page, Clapton, all the greats play this one. The lick itself is simple, but it takes practice to build up the speed. Play this one over and over until you get it down.